TY - CHAP M1 - Book, Section TI - Endocarditis and Other Intravascular Infections A1 - Hareza, Dariusz A1 - Olson, Gregory A1 - Nguyen, Cynthia A1 - Pitrak, David A2 - Schmidt, Gregory A. A2 - Kress, John P. A2 - Douglas, Ivor S. Y1 - 2023 N1 - T2 - Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition AB - KEY POINTSIntravascular infections are characterized by continuous bacteremia, although positive blood cultures are not invariable.Infective endocarditis (IE) has high morbidity and mortality, even with optimal therapy.The diagnosis of IE is clinical, and the modified Duke criteria have been validated and updated.Transesophageal echocardiogram (TEE) is the imaging modality of choice, but a number of imaging techniques may be helpful.Therapy of IE requires parenteral administration of bactericidal antibiotics for an extended duration, although surgical intervention may be also necessary to eradicate the infection or manage complications.Suppurative or septic thrombophlebitis can be a naturally occurring infection or because of local infections, penetrating trauma, injection drug use, or intravenous devices. In addition to antibiotics, anticoagulation may be beneficial.Arterial infections or infectious arteritis occur from septic emboli, seeding of atherosclerotic plaques or aneurysms, trauma, injection drug use, and arterial procedures. Management usually requires surgery, especially in cases with prosthetic vascular grafts. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/09/08 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1201805249 ER -