TY - CHAP M1 - Book, Section TI - Myotonic Dystrophy A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a congenital anomaly of an ionic channel resulting in a multisystemic disease with anomalies of skeletal, smooth, and cardiac muscles. It may cause mental deficiency and alopecia. Clinically, the most obvious features are muscle rigidity and lack of muscle relaxation after contraction. The onset of the disease occurs during early adulthood. However, it may occur at any age and is extremely variable in degree of severity. Progression of the disease is slow, sometimes evolving over 50 to 60 years. There appear to be at least two forms. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164079869 ER -