TY - CHAP M1 - Book, Section TI - Mesomelia-Synostoses Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is part of a spectrum of diseases called osteochondrodysplasia and is associated with a contiguous gene deletion syndrome. Mesomelic shortness of stature is due to severe skeletal changes in the vertebrae, ankles, knees, and elbows. Patients affected present agenesis of the palate, broad nose, and a small mouth. Other radiological features include progressive intracarpal or intratarsal bone fusion, and fusion of metacarpal bones with proximal phalanges. The presence of ptosis, hypertelorism, abnormal soft palate, congenital heart defect, and ureteral anomalies complete the clinical presentation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/04 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164078455 ER -