TY - CHAP M1 - Book, Section TI - LEOPARD Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is an acronym that stands for Lentigines (multiple), Electrocardiographic conduction abnormalities, Ocular hypertelorism, Pulmonary stenosis, Abnormal genitalia, Retardation of growth, and Deafness (sensorineural). It is a complex congenital dysmorphogenetic disorder characterized by skin lesions (lentigines), severe cardiac anomalies (dysrhythmias, pulmonary valve stenosis), ocular hypertelorism, abnormalities of genitalia, sensorineural deafness, and severe retardation of growth. The second most common defects are ventricular septal hypertrophy and pulmonary (or subpulmonary) valve stenosis. The major perioperative complications are severe arrhythmias and/or cardiac decompensation. The presence of nonobstructive asymmetric anteroseptal hypertrophic cardiomyopathy has been reported. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164076681 ER -