TY - CHAP M1 - Book, Section TI - Laron Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas Y1 - 2019 N1 - T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a genetically transmitted endocrine disorder characterized by severe dwarfism. It is associated with a congenital insensitivity to growth hormone (GH). Besides dwarfism, the clinical features include a blue sclerae, hip degeneration, prominent forehead, depressed nasal bridge, micrognathia, truncal obesity, and micropenis. Females have normal sexual character development. Acute hypoglycemia and seizures are often present. As a matter of interest, it was reported in 2011 that individuals affected with this medical condition in Ecuador are resistant to cancer, diabetes mellitus, and to an extent protected against aging. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/09 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164076303 ER -