TY - CHAP M1 - Book, Section TI - Anesthesia for Orthopedic Surgery A1 - Mariano, Edward R. A2 - Butterworth IV, John F. A2 - Mackey, David C. A2 - Wasnick, John D. Y1 - 2018 N1 - T2 - Morgan & Mikhail's Clinical Anesthesiology, 6e AB - KEY CONCEPTS Clinical manifestations of bone cement implantation syndrome include hypoxia (increased pulmonary shunt), hypotension, arrhythmias (including heart block and sinus arrest), pulmonary hypertension (increased pulmonary vascular resistance), and decreased cardiac output. Use of a pneumatic tourniquet on an extremity creates a bloodless field that greatly facilitates surgery. However, tourniquets can produce potential problems of their own, including hemodynamic changes, pain, metabolic alterations, arterial thromboembolism, and pulmonary embolism. Fat embolism syndrome classically presents within 72 h following long-bone or pelvic fracture, with the triad of dyspnea, confusion, and petechiae. Deep vein thrombosis and pulmonary embolism can cause morbidity and mortality following orthopedic operations on the pelvis and lower extremities. Neuraxial anesthesia alone or combined with general anesthesia may reduce thromboembolic complications by several mechanisms, including sympathectomy-induced increases in lower extremity venous blood flow, systemic antiinflammatory effects of local anesthetics, decreased platelet reactivity, attenuated postoperative increase in factor VIII and von Willebrand factor, attenuated postoperative decrease in antithrombin III, and alterations in stress hormone release. For patients receiving prophylactic low-molecular-weight heparin once daily, neuraxial techniques may be performed (or neuraxial catheters removed) 10 to 12 h after the previous dose, with a 4-h delay before administering the next dose. Flexion and extension lateral radiographs of the cervical spine should be obtained preoperatively in patients with rheumatoid arthritis severe enough to require steroids, immune therapy, or methotrexate. If atlantoaxial instability is present, intubation should be performed with inline stabilization utilizing video or fiberoptic laryngoscopy. Effective communication between the anesthesia provider and surgeon is essential during bilateral hip arthroplasty. If major hemodynamic instability occurs during the first hip replacement procedure, the second arthroplasty should be postponed. Adjuvants such as opioids, clonidine, ketorolac, and neostigmine, when added to local anesthetic solutions for intraarticular injection, have been used in various combinations to extend the analgesia duration following knee arthroscopy. Effective postoperative multimodal analgesia facilitates early physical rehabilitation to maximize postoperative range of motion and prevent joint adhesions following knee replacement. Interscalene brachial plexus block with or without a perineural catheter is ideally suited for shoulder procedures. Even when general anesthesia is employed, a peripheral nerve or brachial plexus block can supplement anesthesia and provide effective postoperative analgesia. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/12 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1161430834 ER -