TY - CHAP M1 - Book, Section TI - General Anesthetics and Therapeutic Gases A1 - Patel, Hemal H. A1 - Pearn, Matthew L. A1 - Patel, Piyush M. A1 - Roth, David M. A2 - Brunton, Laurence L. A2 - Hilal-Dandan, Randa A2 - Knollmann, Björn C. Y1 - 2017 N1 - T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e AB - General anesthetics depress the CNS to a sufficient degree to permit the performance of surgery and unpleasant procedures. General anesthetics have low therapeutic indices and thus require great care in administration. The selection of specific drugs and routes of administration to produce general anesthesia is based on the pharmacokinetic properties and on the secondary effects of the various drugs. The practitioner should consider the context of the proposed diagnostic or surgical procedure and the individual patient’s characteristics and associated medical conditions when choosing appropriate anesthetic agents. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/15 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1162536891 ER -