TY - CHAP M1 - Book, Section TI - Formulary A1 - Dershwitz, Mark A1 - Rosow, Carl E. A2 - Longnecker, David E. A2 - Mackey, Sean C. A2 - Newman, Mark F. A2 - Sandberg, Warren S. A2 - Zapol, Warren M. Y1 - 2017 N1 - T2 - Anesthesiology, 3e AB - Table Graphic Jump Location|Download (.pdf)|PrintTABLE A-1. Analgesic AgentsDrugRouteUsual DoseHow SuppliedFormCostaOral COX inhibitorsAcetaminophenPO325-1000 mg325, 500 mgTablet0.01AspirinPO325-650 mg325, 500 mgTablet0.01Celecoxib PO50-400 mg50 mg100 mg200 mg400 mgCapsuleCapsuleCapsuleCapsule0.350.751.231.72DiclofenacPO50-75 mg50 mg75 mgTabletTablet0.210.26DiflunisalPO500-1000 mg500 mgTablet0.92EtodolacPO200-500 mg200 mg300 mg400 mg500 mgCapsuleCapsuleTabletTablet0.540.560.250.35IbuprofenPO200-800 mg200 mg400 mg600 mg800 mgTabletTabletTabletTablet0.010.020.060.05IndomethacinPO25-50 mg25 mgCapsule0.02KetorolacPO10 mg10 mgTablet0.11NaproxenPO250-500 mg250 mg375 mg500 mgTabletTabletTablet0.200.170.10PiroxicamPOPO10-40 mg10 mg20 mgCapsuleCapsule0.780.27SulindacPO150 mg150 mgTablet0.12Oral opioidsCodeinePO30-60 mg30 mg60 mgTabletTablet0.470.86Codeine/acetaminophenPO30-60 mg/300 mg30/300 mg60/300 mgTabletTablet0.210.41Hydrocodone/acetaminophenPO5-7.5 mg/500-1000 mg5 mg/500 mg7.5 mg/750 mgTabletTablet0.410.46HydromorphonePO2-4 mgb2 mgTablet0.34LevorphanolPO2 mgb2 mgTablet1.61MethadonePO10-20 mgb10 mgTablet0.11MorphinePO30-60 mg30 mg10 mg/mL, 5 mLTabletSolution0.350.25Morphine sustained-releasePO30-60 mgb30 mgCaplet2.38OxycodonePO5-10 mg5 mgTablet0.38Oxycodone/acetaminophenPO5-10 mg/325-650 mg5 mg/325 mgCaplet0.17Oxycodone sustained-releasePO10-20 mgb10 mg20 mg40 mg80 mgTabletTabletTabletTablet1.853.536.2711.80TramadolPO50-100 mg50 mgTablet0.11Tramadol/acetaminophenPO75 mg/650 mg37.5 mg/325 mgTablet0.72Transdermal/transmucosal opioids FentanylTransdermal25-100 μg/hour25 μg/hour50 μg/hour75 μg/hour100 μg/hourPatchPatchPatchPatch9.7517.8127.1736.05FentanylTransbuccal200-1600 μg200 μg400 μg800 μgLozengeLozengeLozenge44.3364.35102.92Parenteral COX inhibitorsAcetaminophenIV1000 mg10 mg/mL, 100 mLSolution31.88DiclofenacIV37.5 mg37.5 mg/ mL; 1 mLSolution12.00IbuprofenIV800 mg100 mg/mL, 8 mLSolution11.19KetorolacIVIM30 mg60 mg30 mg/mL, 1 mL30 mg/mL, 2 mLSolutionSolution0.750.39ParecoxibcIV/IM20-40 mg40 mgPowder–cParenteral opioidsAlfentanilIV0.3-3 µg/kg/min500 μg/mL, 5 mLSolution1.14FentanylIV0.5-5 μg/kg50 μg/mL, 2 mL50 μg/mL, 5 mL50 μg/mL, 20 mLSolutionSolutionSolution0.740.404.00HydromorphoneIV/IM0.5-2 mg2 mg/mL, 1 mLSolution0.76MeperidineIV/IM/SC12.5-100 mg100 mg/mL, 1 mLSolution0.65MethadoneIV1-10 mg10 mg/mL, 20 mLSolution185.48MorphineIV/IM/SC1-10 mg10 mg/mL, 1 mLSolution0.53OxymorphoneIV/IM1.5 mg1 mg/mL, 1 mLSolution2.81RemifentanilIV0.01-1 µg/kg/min1 mg2 mg5 mgPowderPowderPowder35.9568.36141.18SufentanilIV0.05-0.5 μg/kg50 μg/mL, 2 mL50 μg/mL, 5 mLSolutionSolution1.922.04Epidural opioidsFentanyldEpiduralEpidural25-100 μg1-4 μg/mL, 5-10 mL/hour50 μg/mL, 2 mLSolution0.74HydromorphonedEpiduralEpidural0.75-1.5 mg10-100 μg/mL, 5-10 mL/hour2 mg/mL, 1 mLSolution0.76Meperidined,eEpidural25-75 mg100 mg/mL, 1 mLSolution0.65MethadoneEpidural1-5 mg10 mg/mL, 20 mLSolution185.48MorphineEpidural2-5 mg0.5 mg/mL, 10 mLSolution, preservative-free1.72SufentanilEpidural20-50 μg50 μg/mL, 2 mLSolution1.92Intrathecal opioidsFentanyld10-25 μg50 μg/mL, 2 mLSolution0.74Meperidined,e10-20 mg100 mg/mL, 1 mLSolution0.65Morphine0.25-0.5 mg0.5 mg/mL, 10 mLSolution, preservative-free1.72Sufentanild3-10 μg50 μg/mL, 2 mLSolution1.92Opioid agonist/antagonistsBuprenorphineIV0.3 mg0.3 mg/mL, 1 mLSolution5.63ButorphanolIV/IMNasal0.5-2 mg1-2 mg (1-2 sprays)2 mg/mL, 1 mL10 mg/mL, 2.5 mLSolutionSolution2.7059.45NalbuphineIV/IM5-10 mg10 mg/mL, 1 mLSolution1.02Opioid antagonistsAlvimopanPO6-12 mg12 mgTablet102.89MethylnaltrexoneSC8-12 mg20 mg/mL, 0.6 mLSolution64.85NaloxegolPO25 mg25 mgTablet7.49NaloxoneIV/IM0.04-1 mg0.4 mg/mL, 1 mLSolution4.57NaltrexonePO50 mg50 mgTablet1.89Opioid adjunctsCarbamazepinePO200-400 mg200 mgTablet0.07GabapentinPO300-600 mg300 mgCapsule0.03PregabalinPO50-100 mg50 mgCapsule1.70aReflects the cost to a hospital that is part of a large buying group for the size and form listed.bMuch higher doses are commonly used in opioid-tolerant patients.cAlthough widely used in many countries, this medication is unlikely to become approved by the FDA in the United States.dNot approved by the FDA for this indication in the United States.eThe required preservative-free preparation rarely is available in the United States. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1144131097 ER -