TY - CHAP M1 - Book, Section TI - The Role of Nonopioid Analgesic Infusions in the Management of Postoperative Pain A1 - De Oliveira, Gildasio S. A1 - Benzon, Honorio T. A1 - White, Paul F. A2 - Hadzic, Admir Y1 - 2017 N1 - T2 - Hadzic's Textbook of Regional Anesthesia and Acute Pain Management, 2e AB - Opioids are the most commonly used medications for perioperative pain control. However, opioid-related side effects such as constipation, nausea, vomiting, and respiratory depression often accompany the use opioids. Many studies have evaluated the efficacy of nonopioids such as ketamine, lidocaine, naloxone, and magnesium as perioperative infusions to decrease postoperative pain and minimize the use of opioids after surgery. Infusions of the short-acting beta-blocker esmolol and the α2 agonist dexmedetomidine have also been investigated as adjuvants to reduce the postoperative opioid requirement. In this chapter, the results of the studies on infusions of ketamine, lidocaine, naloxone, esmolol, α2 agonists, and magnesium will be summarized, and recommendations on their clinical applicability as part of perioperative pain management will be made. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1141738470 ER -