TY - CHAP M1 - Book, Section TI - Medical Management of Cancer Pain A1 - Chai, Thomas A1 - Hough, Stuart W. A1 - Portenoy, Russell K. A1 - Koyyalagunta, Dhanalakshmi A1 - Driver, Larry C. A2 - Bajwa, Zahid H. A2 - Wootton, R. Joshua A2 - Warfield, Carol A. Y1 - 2016 N1 - T2 - Principles and Practice of Pain Medicine, 3e AB - Cancer pain is usually caused directly by neoplastic injury to pain-sensitive structures. For this reason, primary antineoplastic therapy, including radiation, chemotherapy, and palliative surgery, should be considered part of an analgesic strategy in some cases. When therapy directed at the tumor is inappropriate, is not feasible, is ineffective, or causes painful therapy-related syndromes, symptomatic analgesic therapies become the overriding concern. Opioid-based pharmacotherapy is the mainstay approach, but adjunctive anesthetic, surgical, psychiatric, and physical modalities may be essential as well (see Chapter 54, Cancer Pain Syndromes). Pharmacologic approaches may be systemic or regional (anesthetic). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1131935385 ER -