TY - CHAP M1 - Book, Section TI - Polycythemia A1 - Passi, Monica A1 - Berrigan, Michael J. A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. Y1 - 2016 N1 - T2 - Anesthesiology Core Review: Part Two Advanced Exam AB - Polycythemia, a chronic myeloproliferative disorder, affects approximately 2.3 per 100,000 persons per year. It is prevalent in all age groups with the highest incidence occurring in the seventh and eight decades. This disorder, arising from a mutation in the JAK2 gene, gives rise to the proliferation of all hematopoietic precursors, with erythrocytosis being the most common manifestation, and leukocytosis and thrombocytosis more rarer presentations. This resultant erythrocytosis leads to abnormally high hematocrit, predisposing patients to hyperviscosity of the blood and a multitude of associated complications. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1135741169 ER -