TY - CHAP M1 - Book, Section TI - Chronic Opioid Dependence and Therapy A1 - Christiansen, Sandy A1 - Freeman, Brian S. A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. Y1 - 2016 N1 - T2 - Anesthesiology Core Review: Part Two Advanced Exam AB - Over the last decade, chronic opioid use has garnered support for the treatment of terminal cancer pain. It also has been prescribed for noncancer pain. However, chronic opioid therapy (COT) is not without risk, or as one might expect, without controversy. Numerous potential ramifications exist, including maintaining nontoxic therapeutic levels that enhance livelihood, minimizing adverse effects, avoiding illicit diversion and abuse, and prescribing within the legal boundaries. Should aberrant use become a problem or if treatment endpoints are not met, alternatives to COT need to be sought for pain management. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1135739043 ER -