TY - CHAP M1 - Book, Section TI - Anterograde Versus Retrograde Lead Placement A1 - Bedder, Marshall D. A2 - Diwan, Sudhir A2 - Staats, Peter S. PY - 2015 T2 - Atlas of Pain Medicine Procedures AB - The discussion for an anterograde approach versus a retrograde approach to lead placement for spinal cord stimulation (SCS) has evolved in relationship to optimal coverage for pelvic pain conditions. Early attempts to treat bladder pain focused on retrograde placement of SCS leads to the S3 foramen. Unfamiliarity of many practitioners with this technique, the more difficult technical aspects, and the variable anatomy of the sacrum have all posed challenges to this approach. Anterograde placement with lead positioning at the T10-T12 levels has shown great promise in pelvic pain structure coverage. It is now known that retrograde placement is actually a peripheral nerve stimulation performed within the spinal canal by stimulating specific sacral nerves. Whereas anterograde placement is true spinal cord stimulation giving rise to stimulation paresthesia not only in the pelvic distribution but also in the lower extremities. Anterograde stimulation produces an electrical field at the spinal cord activating all known mechanisms of action, whereas it is highly unlikely that peripheral nerve stimulation activates as many different mechanisms of action. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1107200397 ER -