TY - CHAP M1 - Book, Section TI - Frank–Starling Law A1 - Ionescu, Adrian M. A1 - DeGroot, Kerry A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. PY - 2014 T2 - Anesthesiology Core Review: Part One Basic Exam AB - Cardiac output (CO) is dependent on the product of two variables, heart rate (HR) and stroke volume (SV), or the volume pumped by the heart with each contraction. The relationship between CO, HR, and SV can be summarized by the following equation: CO = SV × HR. While the intrinsic HR is dependent on the depolarization of the sinoatrial (SA) node, SV is dependent on three factors: ventricular preload, aortic afterload, and the strength of the myocardial contraction. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1102569374 ER -