TY  - CHAP
M1  - Book, Section
TI  - Protein C Deficiency
A1  - Bissonnette, Bruno
A1  - Luginbuehl, Igor
A1  - Marciniak, Bruno
A1  - Dalens, Bernard J.
PY  - 2006
T2  - Syndromes: Rapid Recognition and Perioperative Implications
AB  - Congenital  or  acquired  control  of  the  clotting  mechanism  resulting  in  a  widespread  thrombotic  tendency.  Protein  C  is  a  vitamin  K-dependent  serine  protease  zymogen  that  selectively  inhibits  factors  Va  and  VIII:C  in  human  plasma,  and  thus  has  an  important  anticoagulant  role.  It  is  associated  with  an  increased  tendency  to  thrombosis.  It  is  either  inherited  or  acquired:  bacterial  sepsis  (especially  of  meningococcal  origin),  hepatic  disease,  disseminated  intravascular  coagulation,  l-asparaginase  therapy,  nephrotic  syndrome,  conditioning  therapy  in  bone  marrow  transplantation,  warfarin-induced  skin  lesions.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=58084033
ER  -