TY - CHAP M1 - Book, Section TI - Ornithine Carbamoyltransferase Deficiency (OTCD) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Marciniak, Bruno A1 - Dalens, Bernard J. PY - 2006 T2 - Syndromes: Rapid Recognition and Perioperative Implications AB - Rare genetic disorder characterized by complete or partial lack of the enzyme ornithine transcarbamylase (OTC). Lack of the enzyme results in excessive hyperammonemia, which is known as a neurotoxin. Clinically, patients present vomiting, refusal to eat, progressive lethargy, and coma. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=58082146 ER -