TY - CHAP M1 - Book, Section TI - Chapter 35. Effects of Mechanical Ventilation on Control of Breathing A1 - Georgopoulos, Dimitris A2 - Tobin, Martin J. PY - 2013 T2 - Principles and Practice of Mechanical Ventilation, 3e AB - The main reasons for instituting mechanical ventilation are to decrease the work of breathing, support gas exchange, and buy time for other interventions to reverse the cause of respiratory failure.1 Mechanical ventilation can be applied in patients who are making or not making respiratory efforts, whereby assisted or controlled modes of support are used, respectively.1 In patients without respiratory efforts, the respiratory system represents a passive structure, and thus the ventilator is the only system that controls breathing. During assisted modes of ventilator support, the patient’s system of control of breathing is under the influence of the ventilator pump.2–4 In the latter instance, ventilatory output is the final expression of the interaction between the ventilator and the patient’s system of control of breathing. Thus, physicians who deal with ventilated patients should know the effects of mechanical ventilation on control of breathing, as well as their interaction. Ignorance of these issues may prevent the ventilator from achieving its goals and also lead to significant patient harm. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/10/12 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=57071823 ER -