TY - CHAP M1 - Book, Section TI - Chapter 14. Extrapleural Pneumonectomy A1 - Miller, Timothy E. A2 - Barbeito, Atilio A2 - Shaw, Andrew D. A2 - Grichnik, Katherine PY - 2012 T2 - Thoracic Anesthesia AB - In an extrapleural pneumonectomy the lung is removed en bloc, together with parietal and visceral pleura, ipsilateral hemidiaphragm and pericardium, as well as mediastinal lymph nodes.The operation is now reserved almost exclusively for the treatment of mesothelioma. A recent randomized control trial showed no improved survival in patients treated with surgery in the context of trimodal therapy.2-10% of individuals with prolonged asbestos exposure will develop mesothelioma, but more than 80% of mesothelioma patients have a history of exposure to asbestos.The major anesthetic issues are significant blood loss, hemodynamic instability, difficult fluid therapy, risk of cardiac herniation and high probability of dysrhythmias. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=56784704 ER -