TY - CHAP M1 - Book, Section TI - Chapter 61. Nonsteroidal Anti-Inflammatory Drugs A1 - Simon, Lee S. A2 - Warfield, Carol A. A2 - Bajwa, Zahid H. PY - 2004 T2 - Principles & Practice of Pain Medicine, 2e AB - Nonsteroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory, analgesic, and antipyretic agents. They are used to reduce pain, decrease stiffness, and improve function in patients with osteoarthritis (OA), rheumatoid arthritis (RA), and other forms of arthritis. They are also used for the treatment of pain including headache, dysmenorrhea, and postoperative pain.1–3 Whether their effectiveness is solely due to their anti-inflammatory or analgesic effects or other possible mechanisms is not known.4 There are at least 20 different NSAIDs currently available in the United States (Table 61-1). In addition, cyclooxygenase-2 selective inhibitors (COX-2 inhibitors, e.g., celecoxib, rofecoxib), with similar efficacy but significantly decreased gastrointestinal (GI) and platelet effects, are available.5–8 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=3419350 ER -