TY - CHAP M1 - Book, Section TI - Patient-Ventilator Synchrony A1 - Doerschug, Kevin C. A1 - Schmidt, Gregory A. A2 - Schmidt, Gregory A. A2 - Kress, John P. A2 - Douglas, Ivor S. PY - 2023 T2 - Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition AB - KEY POINTSPatient-ventilator asynchrony results from an imbalance between a patient’s respiratory drive and the output from the mechanical ventilator.Patient-ventilator asynchrony is associated with poor patient outcomes including mortality. Postulated mechanisms include excessive work of breathing and lung overdistension.Ventilator waveform analysis is a no-cost and easily employed method to detect patient-ventilator asynchrony and monitor the effectiveness of strategies to mitigate asynchronies.Attempts to normalize arterial blood gas values often increase patient-ventilator asynchrony.Increases in set minute ventilation—ventilator overdrive—decrease respiratory drive and improve synchrony, often with low but acceptable PaCO2. SN - PB - McGraw Hill CY - New York, NY Y2 - 2023/12/07 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1201802981 ER -