TY - CHAP M1 - Book, Section TI - Anesthesia for Renal Transplantation A1 - Meinecke, Barbara A2 - Ellinas, Herodotos A2 - Matthes, Kai A2 - Alrayashi, Walid A2 - Bilge, Aykut PY - 2021 T2 - Clinical Pediatric Anesthesiology AB - FOCUS POINTSCongenital and structural abnormalities are the leading causes of pediatric renal failure.The adult approach, curvilinear incision and retroperitoneal placement of the donor kidney, is the current surgical technique.Careful review of preoperative medications is warranted, especially angiotensin converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) that may affect cardiac hemodynamics intraoperatively.Vascular access can be a challenge and may require a preoperative placement in the interventional radiology suite for successful placement.Sugammadex has been proven to be safe and effective in patients with renal failure, perhaps with slower recovery compared with patients with normal renal function. Sugammadex and sugammadex-rocuronium complexes are cleared by hemodialysis.Providing optimal hemodynamics for graft reperfusion is extremely important; this goal can be accomplished with the administration of crystalloid, colloid, blood products, and/or inotropic infusions.Causes of graft loss in the immediate postoperative period include primary nonfunction of the new organ and thrombosis of vessels.Malignancy is a potential complication after transplant surgery with post-transplant lymphoproliferative disease (PTLD) being the most common, developed from latent Epstein–Barr virus (EBV). SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1176458825 ER -