TY - CHAP M1 - Book, Section TI - Lyell Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a severe allergic syndrome caused by an allergic reaction (hypersensitivity) to pharmacological agents, infections, or illnesses such as lymphoma and graft-versus-host disease. It is characterized by extensive bullous eruption of the skin and mucous membranes fever, malaise, conjunctivitis, and diffuse erythema. Complications include severe dehydration with cardiovascular shock, sepsis, pneumonia, and ultimately multiple organ failure. It is often lethal in children with a mortality rate established between 20 and 50%. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164077308 ER -