TY - CHAP M1 - Book, Section TI - Alpers Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - A progressive mitochondrial disorder that predominantly affects the gray matter of the brain and is characterized by the clinical triad of progressive developmental delay, intractable seizures, and liver failure. The prognosis is generally poor and exacerbations can be triggered by stress or infections. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1164061384 ER -