TY - CHAP M1 - Book, Section TI - Antimicrobials A1 - Gritsenko, Diana A1 - Fedorenko, Marianna A1 - Ramesh, Navitha A1 - Ghezel-Ayagh, Anousheh A2 - Go, Ronaldo Collo PY - 2019 T2 - Critical Care Examination and Board Review AB - It has been reported that for every 1-hour delay of effective antimicrobial therapy in patients with septic shock, there is a 7.6% decrease in survival.1,2 Inadequate empiric therapy has also been associated with increased length of hospital stay.3,4 In addition to timing and choice of antimicrobials, understanding the pharmacokinetics is vital to providing adequate coverage while minimizing resistance.5 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1160187300 ER -