TY - CHAP M1 - Book, Section TI - Hypercarbic Respiratory Failure A1 - Braman, Sidney A1 - Feinsilver, Steven H. A2 - Go, Ronaldo Collo PY - 2019 T2 - Critical Care Examination and Board Review AB - The main function of the lung is gas exchange: the elimination of carbon dioxide (CO2) and the delivery of oxygen (O2) to the tissues. When either function is impaired, the result is respiratory failure. Hypercarbic respiratory failure is a consequence of and is in direct proportion to a reduction of alveolar ventilation. Since the third major alveolar gas, nitrogen (N), is inert, any increase in CO2 is accompanied by a reduction of O2, unless supplemental oxygen is provided. When there is an acute or rapid reduction of alveolar ventilation, the result is acute respiratory acidosis. At other times, chronic respiratory failure can result from chronic lung disease, chest wall disease, or an abnormal respiratory control of ventilation. With such patients, there is often compensation of the hypercarbic respiratory failure and the acidosis may be corrected. This chapter will discuss the physiology of hypercarbic respiratory failure and describe clinical scenarios associated with hypercarbia and their associated management. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1160186250 ER -