TY  - CHAP
M1  - Book, Section
TI  - Protection of the Central Nervous System in Surgical Patients
A1  - Kofke, W. Andrew
A1  - Yandrawatthana, Sukanya
A1  - Kositratna, Guy
A2  - Longnecker, David E.
A2  - Mackey, Sean C.
A2  - Newman, Mark F.
A2  - Sandberg, Warren S.
A2  - Zapol, Warren M.
PY  - 2017
T2  - Anesthesiology, 3e
AB  - KEY  POINTSThe  incidence  of  perioperative  stroke  without  predisposing  factors  is  approximately  0.1%,  but  specific  risk  factors  and  procedures  can  increase  the  risk  by  10-fold  or  more.Cerebrovascular  reserve  refers  to  the  capability  of  the  brain’s  vasculature  to  dilate  in  order  to  compensate  for  perioperative  physiologic  stresses.Attention  to  maintenance  of  a  normal  physiologic  milieu  is  the  first  principle  of  brain-oriented  perioperative  care.Fever  kills  vulnerable  neurons,  and  hypothermia  is  protective  in  cases  of  cardiac  arrest  and  possibly  traumatic  brain  injury.Glycemic  control,  avoiding  severe  hyperglycemia,  improves  outcome  after  severe  critical  illness  and  probably  optimizes  neurologic  outcome.Some  anesthetics  are  neuroprotective,  but  some  anesthetic  drugs  may  have  neurotoxic  potential.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessanesthesiology.mhmedical.com/content.aspx?aid=1144136327
ER  -