TY - CHAP M1 - Book, Section TI - Disposition of Injectate with Common Regional Anesthesia Techniques A1 - Gautier, Philippe A2 - Hadzic, Admir PY - 2017 T2 - Hadzic's Textbook of Regional Anesthesia and Acute Pain Management, 2e AB - The outcome of regional anesthesia technique is ultimately dependent on the distribution of the local anesthetic in the relevant tissue space that contains the nerve(s) of interest. Prior to the introduction of ultrasound in regional anesthesia, our understanding of the disposition of the local anesthetic had been limited due to the lack of technology that could allow such monitoring. This addendum features studies of computed tomographic (CT) images that we painstakingly acquired by the author over a period of nearly 2 decades in attempt to elucidate the disposition of local anesthetic injections with nerve block injections and their relationship to the outcome of regional anesthesia. The maldistribution of local anesthetic associated with block failures and/or complications due to the spillage of local anesthetic to the undesired places, such as, for example, the phrenic nerv and neuraxial space are also demonstrated. A uniquely educational aspect of these images is the relationship of the volume of the injectate and its physical spread in the tissue spaces. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1141730324 ER -