TY - CHAP M1 - Book, Section TI - Post-Intensive Care Syndrome A1 - Lim, Leonard A1 - Soto, Graciela A2 - Oropello, John M. A2 - Pastores, Stephen M. A2 - Kvetan, Vladimir PY - 1 T2 - Critical Care AB - KEY POINTSThe number of patients who survive acute critical illness has increased over the last few years and PICS is more common than previously thought.PICS is new or worsening impairment in physical, mental, or cognitive status arising after critical illness and persisting beyond the acute care hospitalization.These impairments are frequently under recognized and adversely impact daily functioning and the quality of life.Decline in lung function parameters and ICU-acquired weakness are some of the physical impairments that can affect health care resource utilization and short- and long-term outcomes.Neurocognitive impairment spans a wide range of dysfunction and is associated with metabolic abnormalities, hypoxemia, fever, sepsis, pharmacological agents, organ dysfunction, and disrupted sleep.The neuro-psychological impairment encountered after ICU care (eg, anxiety, depression, and PTSD) is not associated with an increased severity of illness but rather to both the subjective and objective aspects of the ICU experience.Strategies to minimize or prevent PICS should start during the ICU stay and address those modifiable risk factors known to be associated with the different aspects of PICS (eg, glycemic control, minimizing sedation, early exercise and mobilization, liberation from mechanical ventilation). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1136418993 ER -