TY - CHAP M1 - Book, Section TI - Neonatal Respiratory Distress Syndrome A1 - Taheripour, Mohebat A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. PY - 2016 T2 - Anesthesiology Core Review: Part Two Advanced Exam AB - Neonatal respiratory distress syndrome (RDS) is a problem most often seen in preterm infants due to a developmental deficiency in pulmonary surfactant. However, infants of mothers with gestational diabetes may develop RDS even born near term. Surfactant production by type 2 alveolar pneumocytes occurs predominantly after 32 weeks of gestation. If surfactant is inadequate, hyaline membranes form in the distal bronchioles and alveoli, leading to respiratory insufficiency. The severity of RDS depends upon with the degree of pulmonary immaturity of the lungs and may be worsened by concomitant factors such as infection or oligohydramnios. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/03 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1135742524 ER -