TY - CHAP M1 - Book, Section TI - Ion Channel Myopathies A1 - Sedghi, Kia A1 - Go, Ramon A1 - Berger, Jeffrey A2 - Freeman, Brian S. A2 - Berger, Jeffrey S. PY - 2016 T2 - Anesthesiology Core Review: Part Two Advanced Exam AB - Ion channel myopathies consist of disorders featuring paralysis and hypotonia. Unlike myotonic dystrophy or other causes of myopathies, ion channel myopathies are a group of genetic defects in sodium, chloride, and calcium ion channels that are present in the myocyte membranes, leading to myotonia. Myotonic disorders have multiple etiologies and some disorders may be considered a channelopathy if ion channel conductance is the culprit in the disease, but the most common cause myotonia is not due to an ion channelopathy but a defect in the protein kinase production. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1135741724 ER -