TY - CHAP M1 - Book, Section TI - Ventilator-Induced Lung Injury A1 - Hess, Dean R. A1 - Kacmarek, Robert M. PY - 2014 T2 - Essentials of Mechanical Ventilation, 3e AB - ObjectivesDiscuss the primary factors that contribute to ventilator-induced lung injury (VILI).Discuss stress and strain as related to lung injury.Describe mechanisms whereby small tidal volumes and positive end-expiratory pressure (PEEP) modify VILI.Discuss the effect of an inappropriate ventilatory pattern on inflammatory mediator response and the translocation of cells and molecules.Describe the proposed relationship between VILI and multiple organ dysfunction syndrome (MODS).Discuss the clinical outcomes data to support the use of lung protective ventilatory strategies. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessanesthesiology.mhmedical.com/content.aspx?aid=1121735475 ER -