Zellweger Syndrome: Rare, hereditary
disorder characterized by decreased or missing peroxisomes in the liver,
kidney, and brain. It is characterized by facial abnormalities, central nervous
system dysfunctions, ocular problems, and hepatomegaly. Most symptoms present in
development before birth. Newborns have a typical flat face with a high
forehead, hypertelorism, and epicanthal folds. Other symptoms may include
hypotonia, dysphagia, seizures, congenital heart defects, hepatomegaly,
and/or vision abnormalities such as cataracts.