Normally, it involves the skin
(photosensitivity, skin hypoplasia, increased patchy skin pigmentation, decreased
or increased irregular skin pigmentation, hyperkeratosis, hemangioma capillary,
telangiectasia skin, neoplasia), eyes (photophobia, optic disc atrophy,
conjunctival telangiectasia, paresis of ocular muscles), and CNS (more
common in XPA and XPD: e.g., abnormality, seizures, areflexia, cerebral cortex
atrophy, microcephaly, deafness, and mental retardation). Other possible features
include ectopic testes and teeth anomalies.