Syndrome present from birth, affecting both sexes, and
characterized by postaxial polydactyly of the hands and feet, hexadactyly
and fusion of fifth and sixth metatarsals and metacarpals, and bony clefts
of the mandibular symphysis. Other features include orodental anomalies,
hypoplastic and dysplastic nails, short stature, micrognathia, small mouth,
and hypoplasia of the larynx. Congenital heart defect may be present.