Patients are often of short stature. In addition to
uveitis, ophthalmic features can include visual loss, retinal detachment, cataract,
and glaucoma. Other features include the central nervous system and cutaneous
origin, including deafness (sensorineural), headache, tinnitus, dysacousis, and
meningism associated with cerebrospinal fluid pleocytosis. Alopecia,
premature graying of hair, and vitiligo are also observed. Onset is generally
in postadolescent life, but two case reports exist in children, the youngest being
4 years old. The condition is treated with high-dose steroids.