Stein-Leventhal Syndrome is a condition that is
usually diagnosed after the expected onset of menstruation. Symptoms can
include amenorrhea or menstrual irregularity, hirsutism in
androgen-dependent regions (face, chest, lower abdomen), upper body obesity
(in 50% of patients), and infertility in patients of childbearing age.
Associated with the obesity, patients frequently have insulin resistance
resulting in adult-onset diabetes. Treatment may include progestins, oral
contraceptives, antiandrogens (including spironolactone), weight reduction,
ovulation-inducing medication, and surgery (laparoscopic ovarian cautery or
laser vaporization).