A very rare inherited disorder characterized by
association of alopecia and seizures.
Alopecia Epilepsy Pyorrhea Mental Subnormality Syndrome.
Association of alopecia, mental subnormality, and
Alopecia is congenital, permanent, and universal.
Periodontal disease is present in all patients. Pigmented nevi can be
Evaluate epilepsy treatment efficacy
(EEG, history). Direct laryngoscopy should be performed carefully to prevent periodontal
bleeding. Epilepsy medications should be given the day of surgery. Consider
anesthetic drug interaction with epileptic treatment.
Shokeir MHK: Universal permanent alopecia, psychomotor epilepsy, pyorrhea
and mental subnormality. Clin Genet