Salt-losing signs can be associated with hypertension, recurrent fever, and hypoglycemia.
Adrenal crisis can occur spontaneously in patients affected with severe adrenal
hyperplasia. It includes various signs (headache, weakness, vomiting, low blood pressure,
dehydration, fever, coma, tachycardia, joint and abdominal pain, weight loss, tachypnea)
and can lead to death. Clinical features can also include genital signs (hypospadias,
masculinizing female sexual characteristics, testicular tumors in adults, virilization,
gynecomastia in adults). Growth is accelerated but adult stature is often short.