Rare congenital association characterized by
hypertelorism, prominent supraorbital ridges, abnormal pinnae, broad nasal
bridge with small nose and mouth, and downward-slanting palpebral fissures.
Brachydactyly with cone-shaped epiphyses, cutaneous syndactyly, flattened
tip of thumbs, splayed “frog” feet with a short hallux and a large gap
between the first and second toes, and lateral curvature of the toes
(clinodactyly on the fifth fingers and broad big toes). Other features
include coarse facies, posterior cleft palate, and conduction deafness. The
skull and limb are most often abnormal.