Males have dense nuclear cataracts and
microcorneas, whereas heterozygous females have posterior Y-sutural
cataracts, small corneas, and only slightly reduced vision. Teeth show
nonsyphilitic hutchinsonian incisors, supernumerary teeth, irregular
diastema, and cone-shaped incisors. Dolichocephaly and mandibular
prognathism occur, with a high nasal bridge, prominent, anteverted pinnae,
and short metacarpals. Developmental delay may be seen. Patients have a
marfanoid habitus, and males are often blind.