++
Absent or decreased eyelashes and eyebrows; visual
loss. Other clinical features include dysplastic and grooved nails and alopecia.
++
Choroidal Atrophy; Alopecia Syndrome.
++
Only two cases described. The
mode of inheritance is uncertain, but mild macular disease in the father who
may be a heterozygote representation of a recessive transmission.
++
Total regional choroidal atrophy and other signs
of ectodermal dysplasia, dysplasia of the nails (grooved), and teeth. Fine
hair, absent or decreased eyelashes, eyebrows. Visual loss must be
suspected. Occasionally syndactyly of fingers.
++
Other than special attention to
protection of the eye and its sensitivity to the light, no specific measures
must be undertaken in the anesthetic care of this patient.
Moloney JB, Blake J, Denham B, et al: Regional choroidal atrophy and
alopecia. A new syndrome.
Acta Ophthalmol 66:272, 1988.
[PubMed: 10994447]