The neonatal or infantile form of Marfan syndrome has similar body
disposition and, in addition, lax skin, scoliosis, adducted thumbs, large
floppy ears, flexion contractures, micrognathia, dolichocephaly, muscle
hypoplasia, ectopia lentis, megalocornea, and deficient subcutaneous fat over
joints. Severe cardiac valve insufficiency and aortic dilatation result in
death during the first 2 years of life.