++
Genetically transmitted anomaly of nails (presence of
white nails).
++
Gorlin Bushkell Jensen Syndrome; Porcelain Nails Disease.
++
Incidence is unknown. Inherited
as an autosomal dominant; however, an autosomal recessive inheritance as
been suggested.
++
Incomplete keratinization in the intermediate part
of the nail plate.
++
Clinical presence of completely white nails,
together with histologic evidence of a defect in the nail plate. Leukonychia
totalis, koilonychia, multiple sebaceous cysts, renal calculi.
++
No specific precautions before
anesthesia and perioperative considerations except for patients receiving
chronic corticosteroid therapy, in whom intraoperative supplementation might
be required.
++
See Table L-2 comparing
leukonychia and other nail discoloration syndromes.
Claudel CD, Zic JA, Boyd AS: Idiopathic leukonychia totalis and partialis
in a 12-year-old patient. J Am Acad Dermatol 44(suppl):379, 2001.
Frydman M, Cohen HA: Leukonychia totalis in two sibs.
Am J Med Genet 47:540, 1993.
[PubMed: 8256820]