Microcephaly and retinal and cerebral dysplasia, more commonly
found in premature infants and single infants of multiple birth. Ocular
findings include microphthalmos, enophthalmos, persistence of the primary vitreous, intraocular
hemorrhages, retinal choroid and optic nerve malformations, glaucoma, cataracts, strabismus, retinal
atrophy, and blindness. Hyperplasia or aplasia of the cerebrum and
cerebellum can occur, resulting in hydrocephalus and mental retardation.