Oculocutaneous Albinism: Group of autosomal recessive inherited
diseases divided into three different types. OCA type I primarily presents with
complete absence of pigment in the skin, the hair, and the eyes. All forms
of OCA type I present with photophobia, moderate-to-severe reduced visual
acuity, and nystagmus. The incidence in the general population is estimated
at 1:40,000. OCA type II presents with incomplete absence of skin, hair, and eye
pigmentation. Many patients have pigmented freckles, lentigines, and/or nevi
with age. The ocular presentations are similar to those in OCA type I. OCA type III
presents with minimal pigment reduction in the skin, hair, and eyes. It has
been genetically confirmed only in dark-skinned individuals of African
descent. The ocular presentations are similar to those in OCA type I, but
they are not as severe. The incidence in the general population is unknown.