Based on clinical presentation and radiologic
confirmation of the characteristic malformed limbs. The affection is
asymmetrical and highly variable in its clinical expression. Males are
affected more often, and usually the upper limb and the right side are more
commonly malformed. Some of the more common malformations encountered are
amelia of the arm, peromelia of the upper arm, humeroradial synostosis,
peromelia of the femur, missing fingers, defect of the ulna or ulnar rays,
and hypoplasia of the fibula.