Ectodermal dysplasia may present with sparse and
thin scalp hair, eyebrows and eyelashes, partial anodontia, and small,
widely spaced teeth. Ectrodactyly of the upper and lower extremities can be
associated with syndactyly and/or clefting of hand and feet. Hypoplastic
distal phalanx of the index finger with onychodysplasia has been described.
Ocular fundus examination reveals presumably progressive macular dystrophy
and optic nerve changes. Sweating seems to be unaffected. Mild developmental
delay may occur.