Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + At a Glance Download Section PDF Listen ++ Inherited condition affecting skin, eyes and digits. + Synonym Download Section PDF Listen ++ CASS. + Incidence and Genetic Inheritance Download Section PDF Listen ++ Described in only one family with 5 affected siblings on Rodrigues Island in the Indian ocean (approximately 1600 km east of Madagascar). Autosomal recessive. + Clinical Aspects Download Section PDF Listen ++ Sclerodactyly, hyperkeratosis, digital contractures, and pseudo-Ainhum syndrome (digital constriction bands with autoamputation) associated with cataract and total alopecia. + Anesthetic Considerations Download Section PDF Listen ++ Anesthesia in this condition has not been described. Theoretically, the digital features may limit the patient's ability to activate certain devices, such as a pump for patient controlled analgesia. + Other Condition to Be Considered Download Section PDF Listen ++ Ainhum: A narrow strip of hardened skin with constricting ring formation on the little toe at the level of digitoplantar fold progressively leading to spontaneous amputation. + References Download Section PDF Listen ++Wallis C, Ip FSL, Beighton P: Cataracts, alopecia, and sclerodactyly: A previously apparently undescribed ectodermal dysplasia syndrome on the island of Rodrigues. Am J Med Genet 32:500, 1989. [PubMed: 2773993]