Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + At a Glance Download Section PDF Listen ++ Disorder that results in the combination of teeth and nail anomalies with hypohidrosis. + Incidence and Genetic Inheritance Download Section PDF Listen ++ Extremely rare, autosomal dominant inherited disorder described in two families. + Clinical Aspects Download Section PDF Listen ++ Hypoplastic, hypocalcified enamel of teeth; onycholysis and subungual hyperkeratosis; hypohidrosis. + Anesthetic Considerations Download Section PDF Listen ++ Obtain history and document loose teeth. Careful direct laryngoscopy is required to prevent damage to fragile teeth. Hypohidrosis may result in temperature disturbances, and atropine should be used carefully. + References Download Section PDF Listen ++Witkop CJ Jr, Brearley LJ, Gentry WC Jr: Hypoplastic enamel, onycholysis, and hypohidrosis inherited as an autosomal dominant trait. A review of ectodermal dysplasia syndromes. Oral Surg Oral Med Oral Pathol 39:71, 1975. [PubMed: 122795]