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Of note, this chapter does not include the perioperative management of anticoagulants, antiplatelets, glucocorticoids, and anticonvulsants, which are treated in separate chapters.


  • Understand pathophysiology of patient’s various comorbidities and deduce if discontinuation of a particular drug would lead to disease progression
  • Consider the possibility of withdrawal with an abrupt cessation of a particular drug
  • Consider possible drug–drug interactions perioperatively
  • Understand anticipated type of surgery, anesthesia, as well as the postoperative course


See Table 9-1.

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Table 9-1 Perioperative Management of Cardiovascular Agents

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